SCHEMBL435341

SCHEMBL435341

CC(=CC=Cc1ccccc1)C(=O)OC(=O)C(C)=CC=Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
LMNA P02545 5/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 3/20 0.49
MCL1 Q07820 1/20 0.49
GLA P06280 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
POLB P06746 1/20 0.47
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
KMT2A Q03164 1/20 0.46
GRIK1 P39086 1/20 0.45
MAOB P27338 1/20 0.45
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
AKR1C3 P42330 1/20 0.44
TRPA1 O75762 1/20 0.44
ALOX5 P09917 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4355988 1.00 GAA (0.51) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL35777 0.88 LMNA (0.60) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL8991908 0.88 LMNA (0.60) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL27661303 0.88 GAA (0.45) GAALMNAALDH1A1KDM4EMCL1
Maleic Acid SCHEMBL14249678 0.87 HDAC3 (0.44) GAALMNAALDH1A1KDM4EMCL1
Maleic Acid SCHEMBL9807216 0.86 HCAR2 (0.46) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL10395020 0.85 POLB (0.56) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL5026713 0.85 KMT2A (0.48) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL10395019 0.85 POLB (0.56) GAALMNAALDH1A1KDM4EMCL1
SCHEMBL1034761 0.83 ALDH1A1 (0.65) GAALMNAALDH1A1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236874-B2 Compositions and method for improving the processing of polymer composites 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-07 US claimed
CN-1823130-B Compositions and methods for improving polymer composite processing 3M INNOVATIVE PROPERTIES CO 2010-06-09 CN claimed
US-20090020914-A1 COMPOSITIONS AND METHOD FOR IMPROVING THE PROCESSING OF POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY 2009-01-22 US claimed
US-7402625-B2 Compositions and method for improving the processing of polymer composites 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-07-22 US claimed
EP-1636309-B1 COMPOSITIONS AND METHOD FOR IMPROVING THE PROCESSING OF POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES CO (US) 2008-05-14 EP claimed
CN-101128542-A Polymer blends 3M INNOVATIVE PROPERTIES CO (US) 2008-02-20 CN claimed
EP-1856209-A1 POLYMER BLENDS 3M Innovative Properties Company (US) 2007-11-21 EP claimed
WO-2006091768-A1 POLYMER BLENDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-31 WO claimed
US-20060189756-A1 POLYMER BLENDS 3M INNOVATIVE PROPERTIES COMPANY 2006-08-24 US claimed
CN-1823130-A Compositions and methods for improving polymer composite processing 3M INNOVATIVE PROPERTIES CO (US) 2006-08-23 CN claimed
US-20040254268-A1 Compositions and method for improving the processing of polymer composites 3M INNOVATIVE PROPERTIES COMPANY 2004-12-16 US claimed
EP-1551885-B1 PROCESS TO MODIFY POLYMERIC MATERIALS 3M INNOVATIVE PROPERTIES CO (US) 2016-02-17 EP disclosed
US-8236874-B2 Compositions and method for improving the processing of polymer composites 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-07 US disclosed
US-8101711-B2 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-24 US disclosed
CN-1823130-B Compositions and methods for improving polymer composite processing 3M INNOVATIVE PROPERTIES CO 2010-06-09 CN disclosed
WO-2005003228-A1 COMPOSITIONS AND METHOD FOR IMPROVING THE PROCESSING OF POLYMER COMPOSITES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-13 WO disclosed
US-20040254268-A1 Compositions and method for improving the processing of polymer composites 3M INNOVATIVE PROPERTIES COMPANY 2004-12-16 US disclosed
WO-2004012858-A1 A CONTINUOUS PROCESS FOR THE PRODUCTION OF COMBINATORIAL LIBRARIES OF MODIFIED MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-12 WO disclosed
WO-2004013189-A2 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-12 WO disclosed
US-20040024130-A1 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed