SCHEMBL8043549

SCHEMBL8043549

COC(=O)C(C)=CC=Cc1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.53
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
MAPT P10636 3/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
APP P05067 2/20 0.47
STAT3 P40763 1/20 0.47
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46
MMP13 P45452 1/20 0.46
LMNA P02545 2/20 0.44
AKR1B10 O60218 2/20 0.44
AKR1B1 P15121 2/20 0.44
MAOB P27338 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35777 0.85 LMNA (0.60) ALDH1A1KDM4ELMNAMAOBCYP2C9
SCHEMBL8991908 0.85 LMNA (0.60) ALDH1A1KDM4ELMNAMAOBCYP2C9
SCHEMBL482707 0.84 CA12 (0.44) TYRCA12CA1CA2CA7
SCHEMBL481831 0.81 APP (0.52) TYRCA12CA1CA2CA7
SCHEMBL5606968 0.79 KDM4E (0.55) TYRCA12CA1CA2CA7
SCHEMBL9335450 0.79 KDM4E (0.55) TYRCA12CA1CA2CA7
SCHEMBL10623293 0.79 LMNA (0.54) ALDH1A1KDM4EAPPLMNAMAOB
SCHEMBL10623290 0.79 LMNA (0.54) ALDH1A1KDM4EAPPLMNAMAOB
SCHEMBL1172155 0.78 LMNA (0.53) ALDH1A1KDM4ELMNACYP2C9MEN1
SCHEMBL8924615 0.77 TYR (0.53) TYRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868446-B1 PROCESS FOR PREPARING POLY(4-HYDROXYSTYRENE) TRIQUEST L P (US) 2000-03-22 EP disclosed
EP-0868446-A1 PROCESS FOR PREPARING POLY(4-HYDROXYSTYRENE) HOECHST CELANESE CORPORATION (US) 1998-10-07 EP disclosed
WO-1997013796-A1 PROCESS FOR PREPARING POLY(4-HYDROXYSTYRENE) HOECHST CELANESE CORPORATION (US) 1997-04-17 WO disclosed
US-5578687-A HEATING A CARBINOL UNDER DECOMPOSITION IN THE PRESENCE OF AN ALCOHOL SOLVENT, POLYMERIZATION OF HYDROXYSTYRENE IN VAPOR PHASE HOECHST CELANESE CORPORATION (US) 1996-11-26 US disclosed