Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3583491 | 0.99 | PTGER1 (0.66) | PTGER1ROCK2CYP3A4LMNACYP1A2 | |
| SCHEMBL3579975 | 0.90 | PTGER1 (0.62) | PTGER1ROCK2WNT1GSK3BDYRK1A | |
| SCHEMBL3179566 | 0.89 | PTGER1 (0.64) | PTGER1ROCK2CYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL3575597 | 0.89 | PTGER1 (0.62) | PTGER1ROCK2WNT1GSK3BDYRK1A | |
| SCHEMBL3578834 | 0.89 | PTGER1 (0.81) | PTGER1 | |
| SCHEMBL3177719 | 0.89 | PTGER1 (0.64) | PTGER1ROCK2CYP3A4LMNACYP2C19 | |
| Hydrochloric Acid SCHEMBL3583126 | 0.88 | PTGER1 (0.82) | PTGER1 | |
| Hydrochloric Acid SCHEMBL3176401 | 0.88 | PTGER1 (0.64) | PTGER1CYP3A4WNT1GSK3BDYRK1A | |
| SCHEMBL3190545 | 0.88 | PTGER1 (0.67) | PTGER1CYP3A4LMNATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3169945 | 0.87 | PTGER1 (0.68) | PTGER1CYP3A4WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | claimed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| WO-2008074833-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SCD, SCD5, CYP11B2 | PTGER1 928/4885ROCK2 2537/4885CYP3A4 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.