Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3575597 | 0.99 | PTGER1 (0.62) | PTGER1HTR2CHTR2BHDAC6WNT1 | |
| SCHEMBL3578786 | 0.90 | PTGER1 (0.65) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| Hydrochloric Acid SCHEMBL3583491 | 0.89 | PTGER1 (0.66) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL3179566 | 0.86 | PTGER1 (0.64) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL3177719 | 0.86 | PTGER1 (0.64) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL3190545 | 0.85 | PTGER1 (0.67) | PTGER1HTR2CHTR2BWNT1GSK3B | |
| Hydrochloric Acid SCHEMBL3176401 | 0.85 | PTGER1 (0.64) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| Hydrochloric Acid SCHEMBL3169945 | 0.84 | PTGER1 (0.68) | PTGER1HTR2CHTR2BWNT1GSK3B | |
| SCHEMBL3180838 | 0.83 | PTGER1 (0.61) | PTGER1WNT1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL3178665 | 0.83 | PTGER1 (0.64) | PTGER1WNT1GSK3BDYRK1AMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | claimed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SCD, SCD5, CYP11B2 | PTGER1 928/4885HTR2C 1718/4885HTR2B 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.