Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSC | P53634 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911203 | 1.00 | EPHX2 (0.67) | EPHX2EPHX1USP30CA12CA1 | |
| SCHEMBL356730 | 0.88 | CTSL (0.65) | EPHX2EPHX1USP30CTSLCTSB | |
| SCHEMBL1911333 | 0.85 | RAB9A (0.56) | EPHX2USP30CA12CA1CA2 | |
| SCHEMBL1911204 | 0.83 | RECQL (0.54) | EPHX2USP30CA12CA1CA2 | |
| SCHEMBL14392368 | 0.83 | RECQL (0.54) | EPHX2USP30CA12CA1CA2 | |
| SCHEMBL4123175 | 0.83 | EPHX2 (0.77) | EPHX2EPHX1USP30CA12CA1 | |
| SCHEMBL1912234 | 0.82 | EPHX2 (0.71) | EPHX2EPHX1 | |
| SCHEMBL4010106 | 0.82 | EPHX2 (0.69) | EPHX2EPHX1USP30CA12CA1 | |
| SCHEMBL1911231 | 0.82 | EPHX2 (0.62) | EPHX2EPHX1USP30CTSLCTSB | |
| SCHEMBL24381758 | 0.81 | MEN1 (0.67) | EPHX2EPHX1USP30CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |