Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Levulinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 10/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL3191898 | 0.91 | MEN1 (0.57) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Succinic Acid SCHEMBL27491383 | 0.89 | MEN1 (0.62) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Succinic Acid SCHEMBL6627654 | 0.89 | CYP3A4 (0.62) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Alpha-Ketoglutaric Acid SCHEMBL15900082 | 0.83 | MEN1 (0.48) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Succinic Acid SCHEMBL5028780 | 0.83 | LMNA (0.48) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Glutarate SCHEMBL17982129 | 0.83 | MEN1 (0.52) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Choline SCHEMBL316506 | 0.82 | LMNA (0.63) | ACHELMNAMEN1KMT2ACYP3A4 | |
| Levulinic Acid SCHEMBL357248 | 0.82 | ALDH1A1 (0.56) | ACHELMNAALDH1A1BBOX1FFAR3 | |
| Succinic Acid SCHEMBL28245312 | 0.82 | CYP3A4 (0.52) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL6627652 | 0.82 | LMNA (0.46) | ACHELMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069901-A | Lignin-based phenolic resin and preparation method thereof | 江苏理文造纸有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-2414476-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. du Pont de Nemours and Company (US) | 2012-02-08 | — | — | EP | claimed |
| US-20120011886-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-01-19 | — | — | US | claimed |
| WO-2010117836-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-14 | — | — | WO | claimed |
| CN-116549541-B | Weight-reducing compound composition and preparation thereof | 北京澳特舒尔保健品开发有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117069901-A | Lignin-based phenolic resin and preparation method thereof | 江苏理文造纸有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116549541-A | Weight-reducing compound composition and preparation thereof | 北京澳特舒尔保健品开发有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-2414476-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. du Pont de Nemours and Company (US) | 2012-02-08 | — | — | EP | disclosed |
| US-20120011886-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-01-19 | — | — | US | disclosed |
| WO-2010117836-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |