Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441765 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL1879421 | 0.88 | KDM4E (0.49) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL3578871 | 0.86 | KMT2A (0.65) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL14047370 | 0.84 | KMT2A (0.50) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL15449064 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL8644046 | 0.81 | KMT2A (0.73) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL30908421 | 0.81 | KMT2A (0.73) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL15321070 | 0.80 | KMT2A (0.43) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL1884436 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2ANPSR1GFER | |
| SCHEMBL28787262 | 0.79 | TERT (0.60) | ALDH1A1KDM4EKMT2ANPSR1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076021-A1 | Organic Compounds | IMASE HIDETOMO | 2010-03-25 | — | — | US | disclosed |
| US-20100076021-A1 | Organic Compounds | IMASE HIDETOMO | 2010-03-25 | — | — | US | disclosed |
| US-20100076021-A1 | Organic Compounds | IMASE HIDETOMO | 2010-03-25 | — | — | US | disclosed |
| EP-2084149-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008058967-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008058967-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076021-A1 | Organic Compounds | CETP, NPC1, LCAT | ALDH1A1 1522/4885KDM4E 2894/4885KMT2A 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.