Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644046 | 1.00 | KMT2A (0.73) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL14617053 | 0.86 | MAPT (0.57) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL28827741 | 0.84 | KMT2A (1.00) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL19243071 | 0.84 | KMT2A (0.75) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL8646714 | 0.83 | KMT2A (0.73) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL3579340 | 0.81 | ALDH1A1 (0.62) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL15449064 | 0.79 | ALDH1A1 (0.60) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL25947756 | 0.79 | ALDH1A1 (1.00) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL28787262 | 0.78 | TERT (0.60) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL14575270 | 0.78 | ALDH1A1 (0.48) | KMT2ANPSR1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |