SCHEMBL3583084

SCHEMBL3583084

CC(C)(C)OC(=O)N1CCC(C(N)CCOc2ccccc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.53
GPR119 Q8TDV5 9/20 0.51
STS P08842 1/20 0.48
KDM4E B2RXH2 1/20 0.48
PKM P14618 1/20 0.48
MMP13 P45452 1/20 0.48
USP30 Q70CQ3 1/20 0.46
YAP1 P46937 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3579342 0.85 GPR119 (0.54) DPP4GPR119STSKDM4EPKM
SCHEMBL28347845 0.82 GPR119 (0.53) DPP4GPR119STSKDM4EPKM
SCHEMBL20615628 0.82 GPR119 (0.53) DPP4GPR119STSKDM4EPKM
SCHEMBL2158159 0.81 GPR119 (0.65) GPR119STSKDM4EPKMYAP1
SCHEMBL6148208 0.78 GPR119 (0.53) DPP4GPR119STSKDM4EPKM
SCHEMBL28045408 0.78 DPP4 (0.58) DPP4GPR119KDM4E
SCHEMBL3580922 0.78 GPR119 (0.56) DPP4GPR119STSKDM4EPKM
SCHEMBL20615705 0.77 GPR119 (0.57) DPP4GPR119STSKDM4EPKM
SCHEMBL2553057 0.77 GPR119 (0.57) DPP4GPR119STSKDM4EPKM
SCHEMBL30702475 0.77 GPR119 (0.57) DPP4GPR119STSKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 DPP4 117/4885GPR119 21/4885STS 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.