Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2936301 | 0.94 | MEN1 (0.35) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL28506135 | 0.93 | MEN1 (0.36) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL302142 | 0.92 | MEN1 (0.37) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Bicarbonate SCHEMBL2229450 | 0.92 | MEN1 (0.34) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Oxalic Acid SCHEMBL29142278 | 0.91 | MEN1 (0.35) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL28948439 | 0.91 | MEN1 (0.36) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL28087150 | 0.91 | MEN1 (0.40) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Propionic Acid SCHEMBL508029 | 0.91 | MEN1 (0.33) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL20338489 | 0.91 | MEN1 (0.36) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Acetic Acid SCHEMBL28802048 | 0.90 | MEN1 (0.38) | MEN1HSP90AA1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661373-A | TATB crystal with fusiform micro-nano hierarchical structure and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-03-21 | — | — | CN | claimed |
| CN-114456019-B | Porous TATB explosive spherulite and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2022-11-15 | — | — | CN | claimed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113683780-B | Antiserum and low-cytotoxicity polyamino acid gene delivery carrier material with membrane penetrating activity and nucleus positioning function | 广州医科大学 | 2022-07-05 | — | — | CN | claimed |
| CN-114456019-A | Porous TATB explosive spherulite and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2022-05-10 | — | — | CN | claimed |
| CN-113683780-A | Antiserum and low-cytotoxicity polyamino acid gene delivery carrier material with membrane penetrating activity and nucleus positioning function | 广州医科大学 | 2021-11-23 | — | — | CN | claimed |
| US-20160365228-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION | 2016-12-15 | — | — | US | claimed |
| US-9449797-B2 | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RESEARCH CORPORATION (US) | 2016-09-20 | — | — | US | claimed |
| US-20140335698-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION (US) | 2014-11-13 | — | — | US | claimed |
| EP-4739742-A1 | LATENT CATALYST AND COATING COMPOSITIONS INCLUDING THE SAME | SWIMC LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2025-05-06 | — | — | US | disclosed |
| CN-119661373-A | TATB crystal with fusiform micro-nano hierarchical structure and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-03-21 | — | — | CN | disclosed |
| WO-2025049313-A1 | LATENT CATALYST AND COATING COMPOSITIONS INCLUDING THE SAME | SWIMC LLC (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-115605525-B | Uretdione-containing compositions that crosslink at low temperatures | 科思创德国股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| US-20140335698-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| EP-2684872-A1 | COMPOUND HAVING HEPTAMETHINE STRUCTURE, SENSITIZING DYE AND PHOTOELECTRIC CONVERSION ELEMENT | Gifu University (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20140005415-A1 | IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS | TEXAS STATE UNIVERSITY-SAN MARCOS (US) | 2014-01-02 | — | — | US | disclosed |
| US-20130291943-A1 | PHOTOELECTRIC CONVERSION ELEMENT | DAI-ICHI KOGYO SEIYAKU CO., LTD (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20120011886-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-01-19 | — | — | US | disclosed |
| WO-2011091131-A2 | ESLICARBAZEPINE ACETATE AND ITS POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | NAAA, NIT2, PAM | MEN1 55/4885HSP90AA1 4241/4885KMT2A 4207/4885 |
| US-20140005415-A1 | IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS | CALCOCO2, MCOLN2, MECP2 | MEN1 689/4885HSP90AA1 4771/4885KMT2A 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.