Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL490858 | 0.92 | LMNA (0.56) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Glycerin SCHEMBL8080968 | 0.92 | LMNA (0.56) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Propylene Glycol SCHEMBL18285762 | 0.92 | TDP1 (0.62) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Propylene Glycol SCHEMBL35797 | 0.92 | TDP1 (0.62) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Glycerin SCHEMBL30753 | 0.92 | LMNA (0.56) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Glycerin SCHEMBL6426113 | 0.92 | LMNA (0.56) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Propylene Glycol SCHEMBL4936361 | 0.92 | TDP1 (0.62) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Glycerin SCHEMBL11595153 | 0.89 | LMNA (0.53) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Propylene Glycol SCHEMBL6135352 | 0.89 | TDP1 (0.59) | TDP1ALDH1A1LMNAUSP2TSHR | |
| Glycerin SCHEMBL4723284 | 0.89 | LMNA (0.53) | TDP1ALDH1A1LMNAUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659671-B | Composition in the form of an emulsion | 莱雅公司 | 2021-11-16 | — | — | CN | claimed |
| CN-105979929-B | Composition in the form of an emulsion | 莱雅公司 | 2020-08-21 | — | — | CN | claimed |
| CN-106659672-B | Composition in the form of an emulsion | 莱雅公司 | 2020-04-21 | — | — | CN | claimed |
| EP-0575653-B1 | Process for the increase of strength of the highly permeable capillary hollow membranes | SAECHSISCHE KUNSTSEIDEN GMBH (DE) | 1996-03-13 | — | — | EP | claimed |
| US-20240024221-A1 | COMPOSITION FOR BRIGHTENING AND/OR WHITENING KERATIN MATERIALS | L'OREAL (FR) | 2024-01-25 | — | — | US | disclosed |
| CN-117098807-A | Polymer structure comprising a base plastic with a hydration layer to avoid biofilm formation | 纳米及先进材料研发院有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023194511-A1 | COMPOSITION FOR THE COSMETIC TREATMENT OF KERATIN FIBERS | BIOSYNTHIS (FR) | 2023-10-12 | — | — | WO | disclosed |
| CN-116669686-A | Composition for lightening and/or whitening keratin materials | 莱雅公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4175605-A1 | TWO-PHASE COMPOSITION COMPRISING AN ALKYLPOLYGLYCOSIDE SURFACTANT, A PARTICULAR DIOL AND AN ALKANE, ESTER OR ETHER COMPOUND COMPRISING FROM 15 TO 30 CARBON ATOMS | L'OREAL (FR) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022133715-A1 | COMPOSITION FOR BRIGHTENING AND/OR WHITENING KERATIN MATERIALS | L'OREAL (FR) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022003000-A1 | TWO-PHASE COMPOSITION COMPRISING AN ALKYLPOLYGLYCOSIDE SURFACTANT, A PARTICULAR DIOL AND AN ALKANE, ESTER OR ETHER COMPOUND COMPRISING FROM 15 TO 30 CARBON ATOMS | L'OREAL (FR) | 2022-01-06 | — | — | WO | disclosed |
| CN-106659671-B | Composition in the form of an emulsion | 莱雅公司 | 2021-11-16 | — | — | CN | disclosed |
| EP-2872112-A2 | TWO-PHASE COMPOSITION CONTAINING AN ALKYLPOLYGLUCOSIDE AND AN ESTER WITH A MELTING POINT OF LESS THAN 10°C | L'Oréal (FR) | 2015-05-20 | — | — | EP | disclosed |
| WO-2015062993-A1 | TWO-PHASE COMPOSITION COMPRISING A FATTY ACID ESTER OF SUGAR OR A LIQUID ALKYL POLYGLUCOSIDE, WITH AN HLB < 8, AND A C8-C18 BRANCHED ALKANE | L'OREAL (FR) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015062016-A1 | COMPOSITION IN FORM OF AN EMULSION | L'OREAL (FR) | 2015-05-07 | — | — | WO | disclosed |
| WO-2014013420-A2 | TWO-PHASE COMPOSITION CONTAINING AN ALKYLPOLYGLUCOSIDE AND AN ESTER WITH A MELTING POINT OF LESS THAN 10°C | L'OREAL (FR) | 2014-01-23 | — | — | WO | disclosed |
| EP-2353587-A2 | Antimicrobial compositions and methods | 3M Innovative Properties Co. (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010069995-A1 | SILICONE-FREE TRANSPARENT TWO-PHASE COMPOSITION | L'OREAL (FR) | 2010-06-24 | — | — | WO | disclosed |
| US-7078687-B2 | Thin film analyzing method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20040232330-A1 | Thin film analyzing method | FUJI PHOTO FILM CO., LTD. | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024221-A1 | COMPOSITION FOR BRIGHTENING AND/OR WHITENING KERATIN MATERIALS | KRT18, LMNB2, LMNB1 | TDP1 4176/4885ALDH1A1 2852/4885LMNA 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.