Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546396 | 0.81 | TSHR (0.44) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL9068802 | 0.79 | TSHR (0.43) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| Itaconate SCHEMBL3579855 | 0.78 | ALOX15 (0.52) | TSHRCAMK2ASLC22A6GPR84FFAR1 | |
| SCHEMBL2484913 | 0.77 | EGLN1 (0.36) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| SCHEMBL11856882 | 0.76 | ALOX15 (0.39) | ALOX15HSD17B10 | |
| SCHEMBL28058052 | 0.75 | TSHR (0.58) | TSHRCAMK2ASLC22A6GPR84FFAR1 | |
| SCHEMBL4416067 | 0.74 | ALOX15 (0.40) | ALOX15HSD17B10 | |
| SCHEMBL25232 | 0.73 | ALOX15 (0.46) | ALOX15HSD17B10 | |
| Ethylene Glycol SCHEMBL10967874 | 0.72 | ALOX15 (0.39) | ALOX15HSD17B10 | |
| SCHEMBL8677300 | 0.72 | ALOX15 (0.39) | TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235173-A2 | POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | Novozymes A/S (DK) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009085935-A2 | POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2009-07-09 | — | — | WO | disclosed |