Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL8897172 | 0.89 | ALOX15 (0.54) | ALOX15HSD17B10CAMK2ASLC22A6GPR84 | |
| Adipic Acid SCHEMBL6835410 | 0.87 | ALOX15 (0.60) | ALOX15HSD17B10SLC22A6GPR84FFAR1 | |
| Itaconate SCHEMBL11423524 | 0.85 | ALOX15 (0.58) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Sebacic Acid SCHEMBL9068801 | 0.85 | ALOX15 (0.58) | ALOX15HSD17B10SLC22A6GPR84FFAR1 | |
| Itaconate SCHEMBL5091755 | 0.82 | ALOX15 (0.60) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Itaconate SCHEMBL9328495 | 0.82 | ALOX15 (0.60) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Itaconate SCHEMBL21043626 | 0.82 | ALOX15 (0.60) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Itaconate SCHEMBL216384 | 0.82 | ALOX15 (0.65) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Itaconate SCHEMBL304510 | 0.82 | ALOX15 (0.65) | ALOX15HSD17B10CAMK2AGPR84FFAR1 | |
| Itaconate SCHEMBL27940416 | 0.82 | ALOX15 (0.65) | ALOX15HSD17B10CAMK2AGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235173-A2 | POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | Novozymes A/S (DK) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009085935-A2 | POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2009-07-09 | — | — | WO | disclosed |