Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | ACP3 | P15309 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538108 | 0.98 | PTGS2 (0.61) | PTGS2ACP3TDP1L3MBTL1CYP2D6 | |
| SCHEMBL2871540 | 0.86 | HDAC3 (0.48) | PTGS2ACP3TDP1L3MBTL1SMN1; SMN2 | |
| Diphenylacetic Acid SCHEMBL38022 | 0.85 | SRC (0.62) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL8513250 | 0.85 | SRC (0.62) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL9485695 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL28446280 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL8411440 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL30803718 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL6852183 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC | |
| Diphenylacetic Acid SCHEMBL418537 | 0.82 | SRC (0.59) | GAATDP1L3MBTL1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714167-B2 | Catalytic asymmetric epoxidation | UNIVERSITY OF CHICAGO (US) | 2010-05-11 | — | — | US | disclosed |
| US-7714167-B2 | Catalytic asymmetric epoxidation | UNIVERSITY OF CHICAGO (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1706205-B1 | A CATALYTICAL ASYMMETRIC EPOXIDATION | UNIV CHICAGO (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1706205-B1 | A CATALYTICAL ASYMMETRIC EPOXIDATION | UNIV CHICAGO (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-7202371-B2 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202371-B2 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202371-B2 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050159607-A1 | Catalytic asymmetric epoxidation | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203347-A1 | Catalytic asymmetric epoxidation | DUOX1, DUOX2, EPHX2 | PTGS2 260/4885ACP3 1427/4885GAA 2249/4885 |
| US-20050159607-A1 | Catalytic asymmetric epoxidation | DUOX1, DUOX2, EPHX2 | PTGS2 260/4885ACP3 1427/4885GAA 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.