Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581889 | 0.95 | C5AR1 (0.40) | C5AR1CRHR1KMT2AMEN1F10 | |
| SCHEMBL3574217 | 0.93 | MCHR1 (0.37) | C5AR1LPAR1KDM4EKMT2AMEN1 | |
| SCHEMBL3569329 | 0.88 | C5AR1 (0.41) | C5AR1KMT2AMEN1MLYCDF10 | |
| SCHEMBL3583456 | 0.88 | CNR1 (0.38) | C5AR1HPGDKMT2AMEN1HDAC1 | |
| SCHEMBL3579477 | 0.86 | MCHR1 (0.37) | C5AR1LPAR1KDM4EKMT2AMEN1 | |
| SCHEMBL3571746 | 0.86 | SLC2A1 (0.41) | LPAR1KDM4EKMT2AMEN1LPAR5 | |
| SCHEMBL3582130 | 0.85 | CNR1 (0.40) | LPAR1TRPM8LPAR5 | |
| SCHEMBL3571528 | 0.84 | TP53 (0.41) | C5AR1TP53MAPTLPAR1KDM4E | |
| SCHEMBL3574238 | 0.84 | MLYCD (0.35) | C5AR1MLYCDF10TRPM8HSP90AA1 | |
| SCHEMBL3581186 | 0.82 | CNR1 (0.39) | C5AR1HPGDKMT2AMEN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |