Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 14/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574217 | 0.95 | MCHR1 (0.37) | C5AR1F10CHRNA7MEN1KMT2A | |
| SCHEMBL3580332 | 0.95 | C5AR1 (0.35) | C5AR1F10KLKB1MEN1KMT2A | |
| SCHEMBL3569329 | 0.94 | C5AR1 (0.41) | C5AR1F10KLKB1CHRNA7CNR1 | |
| SCHEMBL3583456 | 0.90 | CNR1 (0.38) | C5AR1CNR1MEN1KMT2A | |
| SCHEMBL3579477 | 0.88 | MCHR1 (0.37) | C5AR1F10CHRNA7MEN1KMT2A | |
| SCHEMBL3571746 | 0.87 | SLC2A1 (0.41) | CNR1MEN1KMT2A | |
| SCHEMBL3582130 | 0.87 | CNR1 (0.40) | CNR1 | |
| SCHEMBL3574238 | 0.85 | MLYCD (0.35) | C5AR1F10KLKB1 | |
| SCHEMBL3571491 | 0.85 | C5AR1 (0.42) | C5AR1F10KLKB1 | |
| SCHEMBL3577569 | 0.85 | C5AR1 (0.42) | C5AR1F10KLKB1CHRNA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |