Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.59 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512419 | 0.81 | CSNK2A1 (0.59) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| Methane SCHEMBL27891504 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL27512420 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL27608547 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL1887268 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL1893419 | 0.80 | MCL1 (0.58) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL31353110 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL8440444 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL29865935 | 0.80 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KDM4E | |
| SCHEMBL27878925 | 0.80 | KDM4E (0.53) | KDM4ETDP1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834010-B2 | Modulators of peripheral 5-HT receptors | SERODUS AS (NO) | 2010-11-16 | — | — | US | disclosed |
| US-20070254874-A1 | Modulators of Preripheral 5-Ht Receptors | BIO-MEDISINSK INNOVASJON (NO) | 2007-11-01 | — | — | US | disclosed |
| EP-1701951-A2 | MODULATORS OF PERIPHERAL 5-HT RECEPTORS | Bio-Medisinsk Innovasjon AS (NO) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061483-A2 | MODULATORS OF PERIPHERAL 5-HT RECEPTORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254874-A1 | Modulators of Preripheral 5-Ht Receptors | HTR4, HTR5A, HTR6 | CSNK2A1 3492/4885CSNK2A2 3466/4885CSNK2B 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.