Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580467 | 1.00 | PGR (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13417362 | 0.81 | TSHR (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13417359 | 0.81 | TSHR (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23950126 | 0.80 | PGR (0.31) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL28695228 | 0.80 | MAPT (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL28675643 | 0.78 | MAPT (0.31) | — | |
| SCHEMBL3583584 | 0.76 | SPHK2 (0.37) | TSHRTDP1 | |
| SCHEMBL3583586 | 0.76 | SPHK2 (0.37) | TSHRTDP1 | |
| SCHEMBL17888811 | 0.75 | TDP1 (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13612892 | 0.69 | PGR (0.31) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
| EP-2069299-A2 | ANESTHETIC COMPOUNDS | Pharmacofore, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008011539-A2 | ANESTHETIC COMPOUNDS | PHARMACOFORE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | OPRL1, OPRM1, CYP3A5 | PGR 3977/4885ADRA2A 312/4885ADRA2B 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.