Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442957 | 1.00 | TOP1 (0.63) | TOP1CA1CA2CA7CA9 | |
| Hydrogen Sulfide SCHEMBL28484519 | 0.97 | TOP1 (0.61) | TOP1CA1CA2CA7CA9 | |
| Sulfur Dioxide SCHEMBL28202805 | 0.93 | CA1 (0.57) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL17265615 | 0.87 | PIM1 (0.66) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL8996375 | 0.87 | TOP1 (0.52) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL29018332 | 0.86 | TOP1 (0.55) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL30492232 | 0.86 | TOP1 (0.55) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL10823285 | 0.82 | MAPT (0.50) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL27657122 | 0.80 | CDC25A (0.52) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL3414850 | 0.78 | TOP1 (1.00) | TOP1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991664-A | Naphthoquinone oxime derivative with antibacterial activity and medical application thereof | 上海交通大学 | 2023-04-21 | — | — | CN | claimed |
| CN-107793380-B | 2, 3-epoxy-2-propyl sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same | 黑龙江八一农垦大学 | 2021-04-23 | — | — | CN | claimed |
| CN-107759538-B | 2, 3-epoxy-2-nonane sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same | 黑龙江八一农垦大学 | 2021-04-23 | — | — | CN | claimed |
| CN-107721893-B | 2- naphthalene sulfydryl -5,8- dimethoxy -1,4- naphthoquinone compound and preparation method thereof and drug containing it | 黑龙江八一农垦大学 | 2019-09-24 | — | — | CN | claimed |
| CN-107879958-B | 2- (4- methoxybenzene sulfydryl) -5,8- dimethoxy -1,4- naphthoquinones and preparation method thereof and drug containing it | 黑龙江八一农垦大学 | 2019-07-19 | — | — | CN | claimed |
| CN-107879958-A | Naphthoquinones of 2 (4 methoxybenzene sulfydryl) 5,8 dimethoxy 1,4 and preparation method thereof and the medicine containing it | 黑龙江八农垦大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107721893-A | Naphthoquinone compound of 2 naphthalene sulfydryl, 5,8 dimethoxy 1,4 and preparation method thereof and the medicine containing it | 黑龙江八农垦大学 | 2018-02-23 | — | — | CN | claimed |
| JP-3002390-A | — | — | None | — | — | JP | disclosed |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2023-03-28 | — | — | US | disclosed |
| CN-110891980-B | Radical polymerization control agent and radical polymerization control method | 川崎化成工业株式会社 | 2022-09-30 | — | — | CN | disclosed |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| CN-107759538-B | 2, 3-epoxy-2-nonane sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same | 黑龙江八一农垦大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-107793380-B | 2, 3-epoxy-2-propyl sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same | 黑龙江八一农垦大学 | 2021-04-23 | — | — | CN | disclosed |
| WO-2008018645-A1 | PESTICIDES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-02-14 | — | — | WO | disclosed |
| CN-1827578-A | Anti-tumor naphthoquinone formic acid soft analogues | UNIV SHANGHAI JIAOTONG (CN) | 2006-09-06 | — | — | CN | disclosed |
| CN-1827578-A | Anti-tumor naphthoquinone formic acid soft analogues | UNIV SHANGHAI JIAOTONG (CN) | 2006-09-06 | — | — | CN | disclosed |
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| JP-H032390-A | PRODUCTION OF 5,8-DIMETHOXY-1,4-NAPHTHOQUINONE DERIVATIVE | OSAKA ORGANIC CHEM IND LTD | 1991-01-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | PPOX, NOX4, CROCC | TOP1 4499/4885CA1 1537/4885CA2 1806/4885 |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | PPOX, NOX4, CROCC | TOP1 4499/4885CA1 1537/4885CA2 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.