Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515833 | 0.91 | CHRNA7 (0.44) | CHRNA7CHRNA3HTR3AUGCG | |
| SCHEMBL3530397 | 0.88 | CHRNA7 (0.49) | CHRNA7CHRNA3HTR3A | |
| SCHEMBL373757 | 0.67 | HPGD (0.53) | CHRNA7CHRNA3HTR3A | |
| SCHEMBL1572751 | 0.67 | CHRNA7 (0.45) | CHRNA7CHRNA3HTR3AUGCG | |
| SCHEMBL3518791 | 0.65 | CHRNA7 (0.39) | CHRNA7CHRNA3HTR3AUGCG | |
| SCHEMBL4702484 | 0.65 | CHRNA7 (0.48) | CHRNA7CHRNA3HTR3A | |
| SCHEMBL3518276 | 0.65 | CHRNA7 (0.49) | CHRNA7CHRNA3HTR3A | |
| SCHEMBL3984845 | 0.65 | L3MBTL1 (0.55) | CHRNA7CHRNA3HTR3A | |
| SCHEMBL3518019 | 0.64 | SCD5 (0.62) | — | |
| SCHEMBL4032087 | 0.64 | L3MBTL3 (0.58) | CHRNA7CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212321-A2 | (1,4-DIAZA-BICYCLO[3.2.2]NON-6-EN-4-YL)-HETEROCYCLYL-METHANONE LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, USEFUL FOR THE TREATMENT OF DISEASE | Memory Pharmaceuticals Corporation (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009055437-A2 | (1,4-DIAZA-BICYCLO[3.2.2]NON-6-EN-4-YL)-HETEROCYCLYL-METHANONE LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, USEFUL FOR THE TREATMENT OF DISEASE | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-04-30 | — | — | WO | claimed |