Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 7/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541641 | 1.00 | DUT (0.61) | DUTHSP90AA1MEN1KMT2ABCHE | |
| SCHEMBL8541638 | 1.00 | DUT (0.61) | DUTHSP90AA1MEN1KMT2ABCHE | |
| SCHEMBL8539929 | 0.99 | DUT (0.60) | DUTHSP90AA1MEN1KMT2ABCHE | |
| SCHEMBL1875470 | 0.82 | DUT (0.48) | DUTHSP90AA1BCHENT5E | |
| SCHEMBL8539901 | 0.82 | ALDH1A1 (0.59) | HSP90AA1BCHEALDH1A1LMNAALB | |
| SCHEMBL30976649 | 0.82 | HSP90AA1 (0.52) | DUTHSP90AA1BCHEALDH1A1LMNA | |
| SCHEMBL30976633 | 0.82 | HSP90AA1 (0.52) | DUTHSP90AA1BCHEALDH1A1LMNA | |
| SCHEMBL30976657 | 0.82 | HSP90AA1 (0.68) | DUTHSP90AA1BCHEALDH1A1LMNA | |
| SCHEMBL8539898 | 0.82 | ALDH1A1 (0.59) | HSP90AA1BCHEALDH1A1LMNAALB | |
| SCHEMBL30976640 | 0.81 | HSP90AA1 (0.51) | DUTHSP90AA1BCHEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075924-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-25 | — | — | US | disclosed |
| US-20100075924-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-25 | — | — | US | disclosed |
| US-20100075924-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-25 | — | — | US | disclosed |
| US-7601702-B2 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2009-10-13 | — | — | US | disclosed |
| US-7601702-B2 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2009-10-13 | — | — | US | disclosed |
| US-7601702-B2 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2009-10-13 | — | — | US | disclosed |
| US-20080300216-A1 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300216-A1 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300216-A1 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2008-12-04 | — | — | US | disclosed |
| EP-1701952-A1 | DUTPASE INHIBITORS | Medivir Aktiebolag (SE) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066160-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300216-A1 | Dutpase Inhibitors | DUT, DHODH, POLR2H | DUT 1/4885HSP90AA1 4778/4885MEN1 3105/4885 |
| US-20100075924-A1 | DUTPASE INHIBITORS | DUT, DHODH, CCNO | DUT 1/4885HSP90AA1 4799/4885MEN1 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.