Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 13/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | TK2 | O00142 | 4/20 | 0.52 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539901 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL30976649 | 0.87 | HSP90AA1 (0.52) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL30976633 | 0.87 | HSP90AA1 (0.52) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL30976657 | 0.87 | HSP90AA1 (0.68) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL30976640 | 0.85 | HSP90AA1 (0.51) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL19871075 | 0.84 | ALDH1A1 (0.67) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL1879768 | 0.84 | BCHE (0.45) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL8541641 | 0.82 | DUT (0.61) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL8541638 | 0.82 | DUT (0.61) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL3582941 | 0.82 | DUT (0.61) | ALDH1A1LMNAALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107850-A1 | HALO-DEHYDRO-3'-DEOXYURACIL PHOSPHORAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-0682670-B1 | DEOXYGENATION OF CIS VICINAL DIOLS | RAYLO CHEMICALS INC (CA) | 1998-05-06 | — | — | EP | disclosed |
| US-5410033-A | Deoxygenation of cis vicinal diols to make didehydro dideoxy nucleosidies and synthetic intermediates | TEROCHEM LABORATORIES LIMITED (CA) | 1995-04-25 | — | — | US | disclosed |