Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.69 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607544 | 0.82 | CD274 (0.71) | CD274PDCD1DPP4FOLH1PTGS1 | |
| SCHEMBL29558512 | 0.82 | CD274 (1.00) | CD274PDCD1DPP4FOLH1PTGS1 | |
| SCHEMBL358303 | 0.82 | CD274 (1.00) | CD274PDCD1DPP4FOLH1PTGS1 | |
| SCHEMBL2209528 | 0.81 | DPP4 (0.60) | CD274PDCD1DPP4FOLH1KMT2A | |
| SCHEMBL30084702 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL3793203 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL7107915 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL7194801 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4FOLH1PTGS1 | |
| SCHEMBL4151221 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL25060697 | 0.79 | CD274 (0.62) | CD274PDCD1DPP4FOLH1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582971-B | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113582971-A | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-11008596-B2 | Cytochrome P450 BM3 enzyme variants for preparation of cyclopropanes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20190211367-A1 | VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-11 | — | — | US | disclosed |