SCHEMBL3583145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3590138	0.86	PDGFRB (0.62)	FGFR1PDGFRBPDGFRAFLT3CDK4
	SCHEMBL29813554	0.84	EGFR (0.62)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL10346428	0.81	CDK4 (0.61)	AURKAFGFR1ALKPAK4FLT3
	SCHEMBL27174693	0.80	MAP4K1 (0.73)	AURKAFGFR1ALKJAK3KDR
	SCHEMBL29819702	0.79	BTK (0.52)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL27156485	0.79	BTK (0.52)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL24625516	0.79	WEE1 (0.82)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL26394690	0.79	PDGFRA (0.85)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL24625523	0.79	PDGFRB (0.83)	AURKAFGFR1PDGFRBPDGFRAALK
	SCHEMBL17296027	0.78	WEE1 (0.58)	FGFR1ALKCDK9PAK4FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.