Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 3/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583688 | 0.90 | C5AR1 (0.42) | C5AR1LSSSERPINE1MBTPS1LPAR1 | |
| SCHEMBL3581049 | 0.89 | C5AR1 (0.43) | C5AR1LSSSERPINE1MBTPS1LPAR1 | |
| SCHEMBL3577795 | 0.88 | LMNA (0.38) | C5AR1CCR1MEN1HPGDKMT2A | |
| SCHEMBL3576631 | 0.86 | CNR1 (0.38) | C5AR1LPAR1LPAR5 | |
| SCHEMBL3581174 | 0.85 | LMNA (0.37) | C5AR1CCR1MEN1HPGDKMT2A | |
| SCHEMBL3583612 | 0.84 | KDM4E (0.40) | C5AR1SERPINE1LPAR1LPAR5OPRM1 | |
| SCHEMBL3576382 | 0.83 | STAT3 (0.38) | LPAR1LPAR5FFAR4 | |
| SCHEMBL3584684 | 0.83 | C5AR1 (0.39) | C5AR1LPAR1LPAR5NPC1ALDH1A1 | |
| SCHEMBL3576449 | 0.82 | LPAR1 (0.39) | C5AR1LPAR1LPAR5LPAR2 | |
| SCHEMBL3576767 | 0.79 | SERPINE1 (0.38) | C5AR1SERPINE1OPRM1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |