Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7741745 | 0.89 | ALDH1A1 (0.41) | CYP3A4POLBALDH1A1USP2TDP1 | |
| SCHEMBL2918755 | 0.88 | ALDH1A1 (0.41) | CYP3A4ALDH1A1TDP1KMT2ACYP1A2 | |
| SCHEMBL3593651 | 0.88 | ALDH1A1 (0.41) | CYP3A4POLBALDH1A1USP2TDP1 | |
| SCHEMBL3588320 | 0.87 | ALDH1A1 (0.42) | CYP3A4POLBALDH1A1USP2TDP1 | |
| SCHEMBL3599942 | 0.87 | USP2 (0.41) | CYP3A4POLBALDH1A1USP2TDP1 | |
| SCHEMBL7736189 | 0.85 | DDB1 (0.45) | CYP3A4POLBALDH1A1USP2TDP1 | |
| SCHEMBL3594645 | 0.83 | L3MBTL1 (0.35) | ALDH1A1TDP1KMT2ACYP1A2DDB1 | |
| SCHEMBL3594808 | 0.82 | CYP3A4 (0.36) | CYP3A4ALDH1A1TDP1KMT2ACYP1A2 | |
| SCHEMBL3594804 | 0.82 | CYP3A4 (0.36) | CYP3A4ALDH1A1TDP1KMT2ACYP1A2 | |
| SCHEMBL3592001 | 0.82 | ALDH1A1 (0.41) | CYP3A4ALDH1A1TDP1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | ZHANG HESHENG | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | CCNH, CBR1, CBR3 | CYP3A4 958/4885POLB 4014/4885ALDH1A1 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.