Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143894 | 0.87 | DDB1 (0.49) | DDB1CRBNALDH1A1TPSAB1TPSD1 | |
| SCHEMBL3583758 | 0.85 | CYP3A4 (0.42) | DDB1CRBNALDH1A1USP2CYP3A4 | |
| SCHEMBL3599942 | 0.84 | USP2 (0.41) | ALDH1A1USP2CYP3A4POLBKMT2A | |
| SCHEMBL3588320 | 0.84 | ALDH1A1 (0.42) | DDB1CRBNALDH1A1USP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7741745 | 0.84 | ALDH1A1 (0.41) | DDB1CRBNALDH1A1USP2CYP3A4 | |
| SCHEMBL3593651 | 0.83 | ALDH1A1 (0.41) | DDB1CRBNALDH1A1USP2CYP3A4 | |
| SCHEMBL7742010 | 0.80 | DDB1 (0.43) | DDB1CRBNCYP3A4KMT2AMEN1 | |
| SCHEMBL24921832 | 0.79 | DDB1 (0.40) | DDB1CRBNALDH1A1TDP1CYP1A2 | |
| SCHEMBL5478671 | 0.78 | ALDH1A1 (0.43) | DDB1CRBNALDH1A1CYP3A4KMT2A | |
| SCHEMBL2918755 | 0.77 | ALDH1A1 (0.41) | DDB1CRBNALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417197-B1 | PRODRUGS FORMED WITH ESTERIFICATION AND ACIDIFICATION | GRUENENTHAL GMBH (DE) | 2002-07-09 | — | — | US | disclosed |