Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | SI | P14410 | 1/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | PPIG | Q13427 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602806 | 0.91 | GAA (0.63) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12323562 | 0.87 | GAA (0.63) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL16761916 | 0.87 | GAA (0.63) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5184954 | 0.86 | GAA (0.68) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3709329 | 0.86 | GAA (0.53) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14498356 | 0.86 | GAA (0.53) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL25379842 | 0.85 | GAA (0.72) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14890530 | 0.85 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7294998 | 0.85 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6245341 | 0.84 | GAA (0.66) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149454-B | 3d-4f bionic metal cage and preparation method and application thereof | 兰州大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114796184-B | Compound containing semi-rigid acylhydrazone ligand, and preparation method and application thereof | 兰州大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114796184-A | Compound containing semi-rigid acylhydrazone ligand and preparation method and application thereof | 兰州大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114766485-A | Application of semi-rigid acylhydrazone ligand in herbicide and composite herbicide based on semi-rigid acylhydrazone ligand | 兰州大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114181109-A | Semi-rigid acylhydrazone ligand and preparation method thereof | 兰州大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-114149454-A | 3d-4f bionic metal cage and preparation method and application thereof | 兰州大学 | 2022-03-08 | — | — | CN | disclosed |
| US-7674810-B2 | 1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase | ROCHE PALO ALTO LLC (US) | 2010-03-09 | — | — | US | disclosed |
| CN-101189230-A | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (CH) | 2008-05-28 | — | — | CN | disclosed |
| EP-1879885-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2008-01-23 | — | — | EP | disclosed |
| US-7211278-B2 | Treating method for suppressing hair growth | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211278-B2 | Treating method for suppressing hair growth | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| WO-2006117306-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-09 | — | — | WO | disclosed |
| US-20060252785-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2006-11-09 | — | — | US | disclosed |
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | ABBOTT LABORATORIES | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252785-A1 | Heterocyclic antiviral compounds | EIF2AK2, HAVCR2, POLR2E | GAA 925/4885MGAM 3134/4885SI 2209/4885 |
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | KCNH1, KCNN1, KCNJ2 | GAA 1909/4885MGAM 4645/4885SI 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.