Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591085 | 0.87 | NR1H2 (0.37) | NR1H2NR1H3HSPA9CA9CYP19A1 | |
| SCHEMBL13382907 | 0.78 | HTR6 (0.37) | HSPA9ATAD2HTR6L3MBTL1PDK2 | |
| SCHEMBL5513606 | 0.72 | NR1H2 (0.39) | NR1H2NR1H3HSPA9CA9CYP19A1 | |
| SCHEMBL496554 | 0.72 | PDK2 (0.55) | CA9ATAD2HTR6KMT2AKDM4E | |
| SCHEMBL30539488 | 0.72 | PDK2 (0.55) | CA9ATAD2HTR6KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7276702 | 0.70 | PDK2 (0.53) | CA9ATAD2HTR6KMT2AKDM4E | |
| SCHEMBL3596380 | 0.70 | CA9 (0.40) | CA9CYP19A1HTR6KMT2AKDM4E | |
| SCHEMBL3594074 | 0.70 | CA9 (0.40) | CA9CYP19A1HTR6KMT2AKDM4E | |
| SCHEMBL3600186 | 0.70 | CA9 (0.47) | NR1H2NR1H3CA9ATAD2KMT2A | |
| SCHEMBL21750723 | 0.70 | HSPA9 (0.65) | NR1H2NR1H3HSPA9CYP19A1ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | NR1H2 133/4885NR1H3 153/4885HSPA9 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.