Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564876 | 1.00 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1L3MBTL1MAPT | |
| SCHEMBL11900903 | 0.80 | DHODH (0.41) | ALDH1A1POLBTDP1MAPTKDM4E | |
| SCHEMBL2305521 | 0.80 | CYP2C19 (0.49) | ALDH1A1POLBKDM4EDHODHHDAC6 | |
| SCHEMBL11520863 | 0.80 | ALDH1A1 (0.37) | ALDH1A1POLBTDP1L3MBTL1MAPT | |
| SCHEMBL8989525 | 0.80 | POLB (0.42) | ALDH1A1POLBTDP1MAPTDHODH | |
| SCHEMBL29584789 | 0.79 | MAPT (0.51) | ALDH1A1TDP1L3MBTL1MAPTKDM4E | |
| SCHEMBL19552279 | 0.79 | MAPT (0.51) | ALDH1A1TDP1L3MBTL1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL27956197 | 0.78 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL27695842 | 0.78 | SLC40A1 (0.45) | TDP1DHODHHDAC6GAALMNA | |
| SCHEMBL10178957 | 0.77 | MAPT (0.39) | ALDH1A1TDP1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955469-A | Pyrazole alcohol compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118126023-B | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-119264054-B | Pyrazolecarboxylic acid borneol ester compound and preparation method and application thereof | 安徽中医药大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-119264054-A | Pyrazolecarboxylic acid borneol ester compound and preparation method and application thereof | 安徽中医药大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-118955469-A | Pyrazole alcohol compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118126023-A | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114540846-B | Synthesis method of 1,2, 4-triazolo six-membered nitrogen heterocycle-3-amine | 五邑大学 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2008118790-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-02 | — | — | WO | disclosed |
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
| US-7396935-B2 | Aryl-substituted pyrazole-amide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-08 | — | — | US | disclosed |
| US-7396935-B2 | Aryl-substituted pyrazole-amide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-08 | — | — | US | disclosed |
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-0254623-B1 | AMINOALKYLTHIO TRIAZOLOPYRIDINE OR TRIAZOLOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY USEFUL AS ANTALGICS | LABORATOIRES UPSA (FR) | 1993-06-09 | — | — | EP | disclosed |
| EP-0441718-A1 | Herbicidally active triazolopyridine compounds | RHONE-POULENC AGROCHIMIE (FR) | 1991-08-14 | — | — | EP | disclosed |
| US-4886805-A | Novel aminoalkylthio derivatives of triazolopyridine or triazoloquinoline, the processes for their preparation, and drugs, useful especially as analgesics, in which they are present | Centre D'Activite Et De Recherches Pharmaceutique Industrielle Biologique Medicale (FR) | 1989-12-12 | — | — | US | disclosed |
| EP-0254623-A1 | Aminoalkylthio triazolopyridine or triazoloquinoline derivatives, process for their preparation, medicaments containing them, particularly useful as antalgics | LABORATOIRES UPSA (FR) | 1988-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC40A1, HAMP | ALDH1A1 514/4885POLB 3691/4885TDP1 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.