Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576645 | 0.92 | HSP90AA1 (0.37) | ESRRGNR1H4HSP90AA1ESRRBOPRM1 | |
| SCHEMBL3570650 | 0.91 | CCR9 (0.41) | CCR9ESRRGNR1H4HSP90AA1ESRRB | |
| SCHEMBL3575573 | 0.91 | HSP90AA1 (0.36) | ESRRGNR1H4HSP90AA1ESRRBOPRM1 | |
| SCHEMBL3583608 | 0.91 | ESRRG (0.35) | ESRRGNR1H4HSP90AA1ESRRBOPRM1 | |
| SCHEMBL3576692 | 0.91 | ESRRG (0.37) | CCR9ESRRGNR1H4HSP90AA1ESRRB | |
| SCHEMBL3580209 | 0.87 | MCHR1 (0.40) | CCR9ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3581265 | 0.87 | NR1H4 (0.39) | CCR9ESRRGNR1H4HSP90AA1ESRRB | |
| SCHEMBL3587153 | 0.84 | ESRRG (0.36) | ESRRGNR1H4HSP90AA1ESRRBOPRM1 | |
| SCHEMBL3580374 | 0.83 | ESRRG (0.36) | CCR9ESRRGNR1H4HSP90AA1ESRRB | |
| SCHEMBL1397638 | 0.82 | HCRTR1 (0.37) | CCR9NR1I3HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |