Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585932 | 0.92 | CCR9 (0.36) | HSP90AA1GRM5ESRRGNR1H4ESRRB | |
| SCHEMBL3580374 | 0.91 | ESRRG (0.36) | HSP90AA1GRM5ESRRGNR1H4ESRRB | |
| SCHEMBL3583608 | 0.90 | ESRRG (0.35) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3575573 | 0.90 | HSP90AA1 (0.36) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3570650 | 0.83 | CCR9 (0.41) | HSP90AA1ESRRGNR1H4ESRRBNR1I3 | |
| SCHEMBL3587153 | 0.83 | ESRRG (0.36) | HSP90AA1GRM5ESRRGNR1H4ESRRB | |
| SCHEMBL3576692 | 0.83 | ESRRG (0.37) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3574285 | 0.81 | ESRRG (0.36) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3577133 | 0.81 | CYP51A1 (0.36) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 | |
| SCHEMBL3584126 | 0.81 | ESRRG (0.36) | HSP90AA1ESRRGNR1H4ESRRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |