Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389129 | 0.82 | NPC1 (0.46) | IDH1DAOKMT2AIDO1NPC1 | |
| SCHEMBL358651 | 0.81 | IDH1 (0.57) | IDH1DAOMEN1KMT2A | |
| SCHEMBL11475876 | 0.78 | LTA4H (0.44) | IDH1IDO1 | |
| SCHEMBL4677561 | 0.75 | IDH1 (0.40) | IDH1DAOKMT2A | |
| SCHEMBL901473 | 0.74 | — | — | |
| SCHEMBL9704354 | 0.74 | MAOA (0.42) | IDH1DAOMEN1KMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL4678510 | 0.73 | NR4A2 (0.42) | IDH1 | |
| SCHEMBL4678509 | 0.73 | IDH1 (0.39) | IDH1DAO | |
| Bromide SCHEMBL4677563 | 0.73 | NR4A2 (0.42) | IDH1 | |
| SCHEMBL752997 | 0.73 | KMT2A (0.46) | IDH1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-4870100-A | INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0230018-A2 | Pyrethroide, process for their preparation and their use in combatting parasites as well as precursors for the preparation of these pyrethroids | BASF Aktiengesellschaft (DE) | 1987-07-29 | — | — | EP | disclosed |