Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576670 | 0.93 | MCHR1 (0.38) | MCHR1NAMPTCRHR1CNR1SLC2A1 | |
| SCHEMBL3570653 | 0.90 | CNR1 (0.39) | NAMPTCNR1SLC2A1CETPLMNA | |
| SCHEMBL3580209 | 0.88 | MCHR1 (0.40) | MCHR1BTKCRHR1HDAC8HPGD | |
| SCHEMBL3577185 | 0.86 | LMNA (0.40) | CNR1S1PR1GRK5CDK8S1PR5 | |
| SCHEMBL3573226 | 0.83 | CNR1 (0.37) | NAMPTCNR1SLC2A1S1PR1GRK5 | |
| SCHEMBL3581186 | 0.83 | CNR1 (0.39) | NAMPTCNR1SLC2A1LMNAHDAC8 | |
| SCHEMBL3583456 | 0.82 | CNR1 (0.38) | NAMPTCNR1SLC2A1S1PR1GRK5 | |
| SCHEMBL3579944 | 0.82 | MCHR1 (0.39) | MCHR1CRHR1 | |
| SCHEMBL3586134 | 0.82 | SLC2A1 (0.36) | NAMPTCNR1SLC2A1S1PR1GRK5 | |
| SCHEMBL3574398 | 0.82 | STAT3 (0.37) | NAMPTCNR1SLC2A1S1PR1GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |