SCHEMBL358792

SCHEMBL358792

CCOC(=O)C1C(C=O)C1(C)C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 5/20 0.36
TP53 P04637 1/20 0.35
HTT P42858 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ADRA2A P08913 1/20 0.34
CNR1 P21554 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11291535 1.00 LMNA (0.69) LMNATDP1TSHRMEN1KMT2A
SCHEMBL10952942 1.00 LMNA (0.69) LMNATDP1TSHRMEN1KMT2A
SCHEMBL1150270 1.00 LMNA (0.69) LMNATDP1TSHRMEN1KMT2A
SCHEMBL1150268 1.00 LMNA (0.69) LMNATDP1TSHRMEN1KMT2A
SCHEMBL1150197 0.85 LMNA (0.51) LMNATDP1TSHRMEN1KMT2A
SCHEMBL1150193 0.85 LMNA (0.51) LMNATDP1TSHRMEN1KMT2A
SCHEMBL359355 0.85 LMNA (0.51) LMNATDP1TSHRMEN1KMT2A
SCHEMBL2168536 0.83 LMNA (0.67) LMNATDP1TSHRMEN1KMT2A
SCHEMBL2168541 0.83 LMNA (0.67) LMNATDP1TSHRMEN1KMT2A
SCHEMBL2170337 0.83 LMNA (0.67) LMNATDP1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002849-B1 PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-01-27 EP claimed
EP-0002849-A1 Process for the preparation of di-(halo)-vinyl compounds and di-(halo)-vinyl compounds produced thereby SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-11 EP claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-2412702-B1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL CO (JP) 2014-12-03 EP disclosed
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-1970369-B1 METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-09-25 EP disclosed
US-8461370-B2 Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
US-8263797-B2 Method for producing cyclopropane carboxylic acid compound and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
US-8168816-B2 Method for producing purified formylcyclopropane compound and intermediate of such formylcyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-01 US disclosed
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
EP-2418197-A1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF Sumitomo Chemical Company, Limited (JP) 2012-02-15 EP disclosed
US-4325969-A Cyanovinyl pyrethroids and pesticidal use thereof AMERICAN CYANAMID CO. (US) 1982-04-20 US disclosed
EP-0002849-B1 PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-01-27 EP disclosed
EP-0038575-A2 Cyanovinyl-cyclopropanecarboxylic acids and method of preparing these compounds AMERICAN CYANAMID COMPANY (US) 1981-10-28 EP disclosed
US-4297371-A INSECTICIDES, MITICIDES, AND PESTICIDES; VETERINARY MEDICINE BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4296241-A Preparation of 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1981-10-20 US disclosed
US-4276306-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US disclosed
US-4262117-A INTERMEDIATES FOR INSECTICIDAL-MITICIDAL PYRETHROIDS AMERICAN CYANAMID COMPANY (US) 1981-04-14 US disclosed
EP-0008867-A2 Cyanovinyl pyrethroids, processes for the preparation of these compounds and pesticidal use of the cyanovinyl pyrethroids AMERICAN CYANAMID COMPANY (US) 1980-03-19 EP disclosed
EP-0002849-A1 Process for the preparation of di-(halo)-vinyl compounds and di-(halo)-vinyl compounds produced thereby SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-11 EP disclosed