Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889128 | 0.80 | SRD5A1 (0.46) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL8555101 | 0.80 | SRD5A1 (0.46) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL10889135 | 0.79 | SRD5A1 (0.45) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL11270465 | 0.79 | NOTUM (0.49) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL3588021 | 0.79 | SRD5A1 (0.45) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL8551856 | 0.79 | SRD5A1 (0.45) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL11272489 | 0.79 | SRD5A1 (0.45) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 | |
| SCHEMBL96857 | 0.76 | AADAT (0.48) | SRD5A1CYP11B1CYP11B2CYP19A1DRD2 | |
| SCHEMBL3587653 | 0.76 | POLB (0.38) | MAP2K1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21483549 | 0.75 | SRD5A1 (0.42) | SRD5A1MAP2K1HTR1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | SRD5A1 166/4885MAP2K1 1707/4885HTR1A 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.