Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.38 |
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | DRD4 | P21917 | 7/20 | 0.38 |
| ▸ | DRD3 | P35462 | 7/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587655 | 0.82 | MAP2K1 (0.39) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3602291 | 0.77 | LOXL2 (0.44) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3588020 | 0.76 | SRD5A1 (0.45) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL14277003 | 0.74 | POLB (0.61) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL282756 | 0.70 | KMT2A (0.39) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3605571 | 0.70 | CHRM1 (0.40) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3599798 | 0.70 | ATAD2 (0.46) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9689691 | 0.67 | MAPT (0.41) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL5661091 | 0.66 | CHRM2 (0.67) | POLBCHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL1763875 | 0.65 | DRD2 (0.43) | POLBCHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | POLB 1341/4885CHRM1 94/4885CHRM2 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.