Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589105 | 1.00 | LTA4H (0.48) | LTA4HESR2GAARXFP1FAAH | |
| SCHEMBL3589320 | 0.95 | LTA4H (0.50) | LTA4HESR2GAAHRH3KCNH2 | |
| SCHEMBL3589324 | 0.95 | LTA4H (0.50) | LTA4HESR2GAAHRH3KCNH2 | |
| SCHEMBL3600750 | 0.95 | LTA4H (0.50) | LTA4HESR2GAAHRH3KCNH2 | |
| SCHEMBL3597992 | 0.91 | LTA4H (0.44) | LTA4HESR2GAARXFP1FAAH | |
| SCHEMBL3597998 | 0.91 | LTA4H (0.44) | LTA4HESR2GAARXFP1FAAH | |
| SCHEMBL13436381 | 0.90 | LTA4H (0.61) | LTA4HESR2FAAHHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL3592982 | 0.90 | LTA4H (0.60) | LTA4HESR2FAAHHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL3592985 | 0.90 | LTA4H (0.60) | LTA4HESR2FAAHHRH3KCNH2 | |
| SCHEMBL13436382 | 0.87 | LTA4H (0.62) | LTA4HESR2GAAHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674802-B2 | leukotriene A4 hydrolase inhibitors; biaryl nitrogen-attached heterocycles | DECODE GENETICS, EHF (IS) | 2010-03-09 | — | — | US | disclosed |
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | LTA4H 1/4885ESR2 1449/4885GAA 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.