SCHEMBL358922

SCHEMBL358922

NC(=O)n1cnc(C[C@H](N)C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CPB2 Q96IY4 9/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41
SLC1A3 P43003 1/20 0.41
CPB1 P15086 5/20 0.40
TYR P14679 5/20 0.40
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA3 P42263 1/20 0.39
GRIA4 P48058 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14831326 0.98 CYP1A2 (0.43) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL4727798 0.88 CYP1A2 (0.45) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL4726518 0.88 CYP1A2 (0.45) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL4437439 0.87 SLC7A5 (0.44) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL7001068 0.87 SLC7A5 (0.44) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL503556 0.83 CYP1A2 (0.44) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL27974517 0.83 CYP1A2 (0.46) CYP1A2CPB2ALPIPKMPTGS1
SCHEMBL3808000 0.83 CPB2 (0.42) CYP1A2CPB2SLC1A3CPB1GRIA1
SCHEMBL18074129 0.83 CPB2 (0.42) CYP1A2CPB2SLC1A3CPB1GRIA1
SCHEMBL3003975 0.83 CPB2 (0.41) CYP1A2CPB2ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025048497-A1 NOVEL HISTIDINE AMIDE CHOLESTEROL COMPOUND, AND RNA DELIVERY LIPID NANOPARTICLES COMPRISING SAME 충남대학교산학협력단 2025-03-06 WO claimed
WO-2025043394-A1 KIT FOR FORMING SUPRAMOLECULAR SELF-ASSEMBLY COMPLEX AND USE THEREOF 北京睿创康泰医药研究院有限公司 2025-03-06 WO claimed
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof TREVENA, INC. 2024-01-25 US claimed
WO-2021216529-A1 β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF TREVENA, INC. (US) 2021-10-28 WO claimed
US-20210324005-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof TREVENA, INC. 2021-10-21 US claimed
US-20180010211-A1 ZIRCONIUM EXTRACTANT AND METHOD FOR EXTRACTING ZIRCONIUM SUMITOMO METAL MINING CO., LTD. (JP) 2018-01-11 US claimed
CN-104583427-B Indium extracting agent and indium extracting method 国立大学法人九州大学 2016-09-21 CN claimed
CN-104822851-B Nickel extraction method 国立大学法人九州大学 2016-09-21 CN claimed
CN-105074023-B noble metal and rhenium extracting agent, and method for extracting noble metal and rhenium using same 国立大学法人九州大学 2016-09-14 CN claimed
CN-104540972-B Valuable metal separation method 国立大学法人九州大学 2016-08-24 CN claimed
WO-2010077339-A2 β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF TREVENA, INC. (US) 2010-07-08 WO claimed
EP-2023730-A1 BETULIN DERIVED COMPOUNDS AS ANTI-FEEDANTS FOR PLANT PESTS Valtion Teknillinen Tutkimuskeskus (FI) 2009-02-18 EP claimed
WO-2007141383-A9 BETULIN DERIVED COMPOUNDS AS ANTI-FEEDANTS FOR PLANT PESTS VALTION TEKNILLINEN (FI) 2008-07-17 WO claimed
WO-2007141383-A1 BETULIN DERIVED COMPOUNDS AS ANTI-FEEDANTS FOR PLANT PESTS VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 2007-12-13 WO claimed
US-6949658-B2 Process for producing optically active α-amino acid and optically active α-amino acid amide MITSUBISHI RAYON CO., LTD. (JP) 2005-09-27 US claimed
US-5486595-A Tumor necrosis factor inhibitors CENTECOR, INC. (US) 1996-01-23 US claimed
WO-1995026744-A1 TUMOR NECROSIS FACTOR INHIBITORS CENTOCOR, INC. (US) 1995-10-12 WO claimed
EP-0473700-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1992-03-11 EP claimed
WO-1990014429-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1990-11-29 WO claimed
EP-0371543-A2 Gastrin releasing peptide antagonists MERCK & CO. INC. (US) 1990-06-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210324005-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof ARRB1, ADRB1, FGB CYP1A2 4688/4885CPB2 686/4885ALPI 4805/4885
US-20180010211-A1 ZIRCONIUM EXTRACTANT AND METHOD FOR EXTRACTING ZIRCONIUM ZKSCAN2, ZRANB2, PEF1 CYP1A2 4465/4885CPB2 1699/4885ALPI 1559/4885
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof ARRB1, FGB, SARS1 CYP1A2 4703/4885CPB2 625/4885ALPI 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.