Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3580689 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL2970537 | 0.79 | GAA (0.41) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL13072296 | 0.76 | GAA (0.40) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL3596407 | 0.74 | GAA (0.38) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL3581846 | 0.74 | SMN1; SMN2 (0.39) | GAAATMSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15724295 | 0.72 | KDM4E (0.37) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL18518478 | 0.67 | CASP3 (0.45) | GAAALDH1A1MAPTLMNAHTT | |
| SCHEMBL27174884 | 0.66 | GAA (0.36) | GAAATMSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3580596 | 0.66 | GAA (0.38) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL5983810 | 0.65 | SMN1; SMN2 (0.38) | GAASMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | GAA 4433/4885ATM 3884/4885SMN1; SMN2 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.