Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589942 | 0.90 | KMT2A (0.37) | ALDH1A1NPSR1KMT2AMAP1LC3BTDP1 | |
| SCHEMBL3601478 | 0.89 | MAP1LC3B (0.34) | ALDH1A1KMT2AMAP1LC3BTDP1TSHR | |
| SCHEMBL3599942 | 0.82 | USP2 (0.41) | ALDH1A1KMT2AMAP1LC3BTDP1KDM4E | |
| SCHEMBL3598557 | 0.81 | L3MBTL1 (0.39) | ALDH1A1KMT2AMAP1LC3BTDP1MEN1 | |
| SCHEMBL3595909 | 0.81 | KMT2A (0.42) | ALDH1A1KMT2AMAP1LC3BTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL3584967 | 0.80 | KMT2A (0.41) | ALDH1A1KMT2AMAP1LC3BTDP1MEN1 | |
| SCHEMBL3594340 | 0.80 | NPC1 (0.42) | ALDH1A1KMT2ATDP1NPC1MEN1 | |
| SCHEMBL3594344 | 0.80 | NPC1 (0.42) | ALDH1A1KMT2ATDP1NPC1MEN1 | |
| SCHEMBL24921832 | 0.80 | DDB1 (0.40) | ALDH1A1MAP1LC3BTDP1TSHRL3MBTL1 | |
| SCHEMBL13167677 | 0.79 | NPC1 (0.41) | ALDH1A1KMT2ATDP1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | ZHANG HESHENG | 2010-09-23 | — | — | US | claimed |
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | ZHANG HESHENG | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | CCNH, CBR1, CBR3 | ALDH1A1 2635/4885NPSR1 806/4885KMT2A 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.