Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203883 | 0.88 | ADRB1 (0.36) | CA2CHKAKDM4ESMN1; SMN2HRH1 | |
| SCHEMBL2254566 | 0.82 | CA1 (0.35) | CA2SMN1; SMN2ALDH1A1CA1TP53 | |
| SCHEMBL28394201 | 0.82 | CA1 (0.35) | CA2SMN1; SMN2ALDH1A1CA1TP53 | |
| SCHEMBL2251329 | 0.82 | CA1 (0.35) | CA2SMN1; SMN2ALDH1A1CA1TP53 | |
| SCHEMBL4717441 | 0.82 | CA1 (0.35) | CA2SMN1; SMN2ALDH1A1CA1TP53 | |
| Cyclopropane SCHEMBL28399372 | 0.78 | CA2 (0.41) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| Cyclopropane SCHEMBL28392647 | 0.76 | CA2 (0.39) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL519409 | 0.74 | ALDH1A1 (0.38) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL930605 | 0.71 | — | — | |
| SCHEMBL12671511 | 0.71 | CA2 (0.35) | CA2CHKAKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001358-A | Adjust the new pyridine hepyramine compound of istone lysine demethylase (KDM) catalytic activity | 东亚ST株式会社 | 2017-08-01 | — | — | CN | claimed |
| EP-2118048-A2 | MALE CONTRACEPTIVE | King's College London (GB) | 2009-11-18 | — | — | EP | claimed |
| WO-2008087421-A2 | MALE CONTRACEPTIVE | KING'S COLLEGE LONDON (GB) | 2008-07-24 | — | — | WO | claimed |
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-106279138-B | Aromatic heterocyclic derivatives and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109311868-A | Compound for treating cancer and inflammatory disease | 尚医治疗有限责任公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-105399698-B | Aromatic heterocyclic derivatives and its application in drug | 广东东阳光药业有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-107428749-A | The substituted ylamine compounds of imidazo [1,2 α] pyridine 2 and its pharmaceutical composition and application method | 南京泽宁医药研发有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-106279138-A | Heteroaromatic analog derivative and the application in medicine thereof | 广东东阳光药业有限公司 | 2017-01-04 | — | — | CN | disclosed |
| EP-2118048-B1 | MALE CONTRACEPTIVE | AMOBI NNAEMEKA IKECHUKWU (GB) | 2016-11-23 | — | — | EP | disclosed |
| US-8927579-B2 | Male contraceptive | Amobi, Nnaemkea Ikechukwu (GB) | 2015-01-06 | — | — | US | disclosed |
| US-8778968-B2 | — | — | 2014-07-15 | — | — | US | disclosed |
| US-20100029624-A1 | Male Contraceptive | KING'S COLLEGE LONDON (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-2118048-A2 | MALE CONTRACEPTIVE | King's College London (GB) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008087421-A2 | MALE CONTRACEPTIVE | KING'S COLLEGE LONDON (GB) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029624-A1 | Male Contraceptive | NR5A1, AR, CYP19A1 | CA2 4635/4885CHKA 3698/4885KDM4E 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.