Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590630 | 1.00 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL6138624 | 0.89 | PTGER4 (0.43) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL3601150 | 0.85 | FFAR4 (0.44) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL3601148 | 0.85 | FFAR4 (0.44) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL13443300 | 0.80 | KMT2A (0.42) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL3606150 | 0.77 | KMT2A (0.52) | PTGER1PTGER4PTGER3PTGER2CYP3A4 | |
| SCHEMBL6138566 | 0.76 | PPARG (0.41) | PTGER1PTGER4PTGER3PTGER2HRH3 | |
| SCHEMBL3590675 | 0.75 | FFAR4 (0.47) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9806467 | 0.73 | PTGER1 (0.58) | PTGER1PTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL10964455 | 0.72 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | PC, GOT2, SDHA | PTGER1 633/4885PTGER4 866/4885PTGER3 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.