Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 6/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790207 | 0.88 | TAAR1 (0.47) | TAAR1IDO1AHRPTGS1MAOB | |
| SCHEMBL28757558 | 0.82 | ALDH1A1 (0.48) | TAAR1IDO1MAOBALDH1A1KIF11 | |
| SCHEMBL4811925 | 0.78 | ALDH1A1 (0.48) | MAOBALDH1A1KIF11 | |
| SCHEMBL5779946 | 0.76 | IDO1 (0.40) | IDO1AHRPTGS1MTORALDH1A1 | |
| SCHEMBL6767276 | 0.76 | PTGS1 (0.40) | TAAR1IDO1AHRPTGS1MAOB | |
| SCHEMBL5323954 | 0.74 | TAAR1 (0.50) | TAAR1IDO1MAOBKDM4EALDH1A1 | |
| SCHEMBL7381239 | 0.74 | CACNA1H (0.45) | KDM4EHIF1AKIF11 | |
| SCHEMBL624798 | 0.74 | TAAR1 (0.50) | TAAR1IDO1MAOBKDM4EALDH1A1 | |
| SCHEMBL3633320 | 0.72 | TAAR1 (0.48) | TAAR1IDO1MAOBKDM4EALDH1A1 | |
| SCHEMBL6459927 | 0.72 | AHR (0.68) | AHRPTGS1NQO2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010020-A1 | PHOSPHODIESTERASE 4 INHIBITORS | LIU RUIPING | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010020-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE3B, PDE3A | TAAR1 1215/4885IDO1 1794/4885AHR 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.