Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790207 | 0.83 | TAAR1 (0.47) | PTGS1AHRNQO2CYP1A2TAAR1 | |
| SCHEMBL8366212 | 0.80 | IDO1 (0.39) | PTGS1BACE1IDO1 | |
| SCHEMBL4811925 | 0.78 | ALDH1A1 (0.48) | CYP1A1CYP1B1BACE1MAOB | |
| SCHEMBL5323954 | 0.77 | TAAR1 (0.50) | TAAR1IDO1MAOB | |
| SCHEMBL3590959 | 0.76 | TAAR1 (0.44) | PTGS1AHRNQO2TAAR1IDO1 | |
| SCHEMBL28757558 | 0.74 | ALDH1A1 (0.48) | CYP1A1CYP1B1TAAR1IDO1MAOB | |
| SCHEMBL1992348 | 0.70 | PTGS1 (0.46) | PTGS1AHRNQO2CYP1A1CYP1B1 | |
| SCHEMBL1295918 | 0.68 | RXRA (0.41) | IDO1 | |
| SCHEMBL16225102 | 0.68 | LMNA (0.44) | PTGS1CYP1A2 | |
| SCHEMBL14396108 | 0.68 | IDO1 (0.39) | CLK1DYRK1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787540-B2 | FOR THERAPY OF AUTOIMMUNE DISEASES, ASTHMA, OSTEOPOROSIS, ATHEROSCLEROSIS, ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-09-07 | — | — | US | disclosed |