Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803478 | 1.00 | AHR (0.68) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL6465459 | 1.00 | AHR (0.68) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL13790220 | 0.95 | PTGS1 (0.61) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL22931544 | 0.88 | AHR (0.68) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL13790273 | 0.88 | AHR (0.68) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL13790263 | 0.88 | AHR (0.68) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL18002518 | 0.86 | AHR (0.58) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL29507308 | 0.85 | AHR (0.65) | AHRPTGS1NQO2CYP1A2NFE2L2 | |
| SCHEMBL21064470 | 0.85 | CYP19A1 (0.57) | AHRPTGS1NQO2NFE2L2 | |
| SCHEMBL14363044 | 0.85 | NFE2L2 (0.71) | AHRPTGS1NQO2NFE2L2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418164-A1 | New stilbene derivatives and their use as aryl hydrocarbon receptor ligand antagonists | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-05-12 | — | — | EP | claimed |
| US-20250179435-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-06-05 | — | — | US | disclosed |
| EP-4049665-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDRENS MEDICAL CT CORP (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-3313420-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | CHILDRENS MEDICAL CT CORP (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11891625-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | CHILDREN'S MEDICAL CENTER CORPORATION | 2024-02-06 | — | — | US | disclosed |
| EP-4049665-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | Children's Medical Center Corporation (US) | 2022-08-31 | — | — | EP | disclosed |
| EP-3429603-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDRENS MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |
| US-20200248143-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10669528-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190119642-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017161001-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-09-21 | — | — | WO | disclosed |
| WO-2016210292-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2016-12-29 | — | — | WO | disclosed |
| EP-1585713-A1 | NEW STILBENE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-10-19 | — | — | EP | disclosed |
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.) (FR) | 2004-07-29 | — | — | US | disclosed |
| WO-2004041758-A1 | NEW STILBENE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR LIGAND ANTAGONISTICS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.) (FR) | 2004-05-21 | — | — | WO | disclosed |
| EP-1418164-A1 | New stilbene derivatives and their use as aryl hydrocarbon receptor ligand antagonists | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-05-12 | — | — | EP | disclosed |
| US-20040034063-A1 | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity | KO SOO S (US) | 2004-02-19 | — | — | US | disclosed |
| US-6605623-B1 | Prevention of asthma and other allergic diseases | BRISTOL-MYERS SQUIBB PHARMA CO. | 2003-08-12 | — | — | US | disclosed |
| US-6525069-B1 | Such as N-(t-butyl)-N'-(2-((3-(4-fluorophenyl)methyl)piperi -dinyl)methyl)cyclohexyl)urea; prevention of asthma and other allergic diseases | BRISTOL-MYERS SQUIBB PHARMA CO. | 2003-02-25 | — | — | US | disclosed |
| US-6444686-B1 | FOR THE PREVENTION OF ASTHMA AND OTHER ALLERGIC DISEASES. | BRSITOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200248143-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | HDAC1, EHMT1, MCL1 | AHR 755/4885PTGS1 3097/4885NQO2 3350/4885 |
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | AHR, HCAR3, HCAR1 | AHR 1/4885PTGS1 2187/4885NQO2 1587/4885 |
| US-10669528-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | HDAC1, EHMT1, MCL1 | AHR 755/4885PTGS1 3097/4885NQO2 3350/4885 |
| US-20040034063-A1 | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity | CCR3, CCR1, CCR10 | AHR 745/4885PTGS1 282/4885NQO2 1837/4885 |
| US-20250179435-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | MCL1, HCLS1, KIT | AHR 1844/4885PTGS1 2861/4885NQO2 2069/4885 |
| US-11891625-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | HDAC1, EHMT1, MCL1 | AHR 755/4885PTGS1 3097/4885NQO2 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.