Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | IDO1 | P14902 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397328 | 0.86 | L3MBTL1 (1.00) | L3MBTL1MAPK1KDM4EADORA1NPSR1 | |
| SCHEMBL2187242 | 0.85 | KDM4E (0.72) | L3MBTL1MAPK1KDM4EIDO1ADORA1 | |
| SCHEMBL29051455 | 0.84 | IDO1 (0.80) | L3MBTL1MAPK1KDM4EIDO1LMNA | |
| SCHEMBL29781817 | 0.84 | KDM4E (1.00) | L3MBTL1MAPK1KDM4EIDO1HTT | |
| SCHEMBL12481275 | 0.84 | KDM4E (1.00) | L3MBTL1MAPK1KDM4EIDO1HTT | |
| SCHEMBL2186845 | 0.84 | KDM4E (0.74) | L3MBTL1MAPK1KDM4EIDO1HTT | |
| SCHEMBL29051451 | 0.84 | KDM4E (0.74) | L3MBTL1MAPK1KDM4EIDO1HTT | |
| SCHEMBL5852445 | 0.83 | NPSR1 (0.81) | L3MBTL1MAPK1KDM4EADORA1NPSR1 | |
| SCHEMBL1606606 | 0.83 | LMNA (0.80) | L3MBTL1MAPK1KDM4EADORA1NPSR1 | |
| SCHEMBL3865315 | 0.82 | L3MBTL1 (0.71) | L3MBTL1MAPK1KDM4EADORA1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574048-A | Bromination reaction method of remote indole C-H bond by using sunlight catalysis | 陕西科技大学 | 2023-08-11 | — | — | CN | claimed |
| CN-117603120-A | Preparation method and application of indole-3-fluoroketone compound | 平顶山学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-116574048-A | Bromination reaction method of remote indole C-H bond by using sunlight catalysis | 陕西科技大学 | 2023-08-11 | — | — | CN | disclosed |
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | NR3C1, NR3C2, NR0B1 | L3MBTL1 3816/4885MAPK1 703/4885KDM4E 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.