Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648686 | 0.83 | MGMT (0.54) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1843397 | 0.83 | MGMT (0.54) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14027831 | 0.83 | MGMT (0.54) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8564287 | 0.83 | MGMT (0.61) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1840400 | 0.82 | MGMT (0.53) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26640517 | 0.80 | MGMT (0.51) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3586604 | 0.80 | MGMT (0.51) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26640374 | 0.80 | MGMT (0.51) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29021281 | 0.79 | KMT2A (0.46) | MGMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26640090 | 0.79 | MGMT (0.50) | MGMTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784403-B1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2013-07-17 | — | — | EP | disclosed |
| CN-101010321-B | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP | 2011-10-26 | — | — | CN | disclosed |
| US-7642269-B2 | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-01-05 | — | — | US | disclosed |
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-13 | — | — | US | disclosed |
| CN-101010321-A | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP (KR) | 2007-08-01 | — | — | CN | disclosed |
| EP-1784403-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006038773-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, PPOX | MGMT 4361/4885MEN1 2718/4885KMT2A 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.