Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 20/20 | 1.00 |
| ▸ | MAOA | P21397 | 12/20 | 0.76 |
| ▸ | MAOB | P27338 | 12/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094445 | 0.94 | ALDH2 (0.88) | ALDH2MAOAMAOB | |
| SCHEMBL12940403 | 0.89 | ALDH2 (0.81) | ALDH2MAOAMAOB | |
| SCHEMBL4684681 | 0.86 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL10624708 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL7752699 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320544 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320049 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320035 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL1701078 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL3419148 | 0.85 | ALDH2 (0.74) | ALDH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338624-B2 | Isoflavone derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2012-12-25 | — | — | US | disclosed |
| US-20100069478-A1 | ISOFLAVONE DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO, LTD. (IL) | 2010-03-18 | — | — | US | disclosed |
| US-20100029758-A1 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. | 2010-02-04 | — | — | US | disclosed |
| WO-2008102350-A1 | ISOFLAVONE DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2008-08-28 | — | — | WO | disclosed |
| EP-1484966-A4 | DERIVATIVES OF ISOFLAVONES | YEDA RES & DEV (IL) | 2006-04-05 | — | — | EP | disclosed |
| US-20050096381-A1 | Derivatives of isoflavones | YEDA & MEDICAL RESEARCH | 2005-05-05 | — | — | US | disclosed |
| EP-1484966-A2 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003079965-A2 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-10-02 | — | — | WO | disclosed |
| US-4772627-A | AMORPHOUS DRUG AND ADSORBENT, IMPROVED DISSOLUTION AND ADSORPTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0129893-A2 | Ground mixture | Takeda Chemical Industries, Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029758-A1 | DERIVATIVES OF ISOFLAVONES | GPER1, ESR1, ESR2 | ALDH2 3865/4885MAOA 3660/4885MAOB 2492/4885 |
| US-20050096381-A1 | Derivatives of isoflavones | GPER1, ESR2, ESR1 | ALDH2 2910/4885MAOA 2556/4885MAOB 1516/4885 |
| US-20100069478-A1 | ISOFLAVONE DERIVATIVES AND USES THEREOF | SHBG, CYP19A1, GPER1 | ALDH2 2737/4885MAOA 689/4885MAOB 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.