SCHEMBL4094445

SCHEMBL4094445

O=C(O)COc1ccc(-c2coc3cc(OCC(=O)O)ccc3c2=O)cc1

nearest known ligand 0.88

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH2 P05091 16/20 0.88
MAPT P10636 3/20 0.69
ALDH1A1 P00352 2/20 0.69
MAOA P21397 10/20 0.67
MAOB P27338 10/20 0.67
GAA P10253 1/20 0.67
KDM4E B2RXH2 1/20 0.63
MEN1 O00255 1/20 0.63
HPGD P15428 1/20 0.63
KMT2A Q03164 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3591660 0.94 ALDH2 (1.00) ALDH2MAOAMAOB
SCHEMBL12940403 0.93 ALDH2 (0.81) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL810070 0.88 ALDH2 (0.70) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL810041 0.87 ALDH2 (0.72) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL809969 0.87 ALDH2 (0.72) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL4095148 0.86 MAPT (0.87) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL2107428 0.84 ALDH2 (0.90) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL11421623 0.84 ALDH1A1 (0.69) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL10623016 0.84 ALDH1A1 (0.76) ALDH2MAPTALDH1A1MAOAMAOB
SCHEMBL810042 0.83 ALDH2 (0.63) ALDH2MAPTALDH1A1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2014-04-10 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8217134-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2012-07-10 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
EP-1951260-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM Bezwada Biomedical LLC (US) 2008-08-06 EP disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALDH2 1402/4885MAPT 4117/4885ALDH1A1 1816/4885
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 ALDH2 1613/4885MAPT 2351/4885ALDH1A1 384/4885
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALDH2 1402/4885MAPT 4117/4885ALDH1A1 1816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.